Replication issues with multiple databases

I am planning to use replication from 400 databases to the master database on
a periodic basis. Do you see any issues with that ?
All databases have the same structure
Alu,
this is a bit vague as it stands but certainly this is 'possible'. In
this link they discuss scaling merge to 2000 subscribers:
http://www.microsoft.com/technet/pro...mergperf.mspx.
For your setup, the type of replication selected will have some
implications. There are also implications with the type of topology
selected, hardware available, bandwidth, data volume etc so really you just
have to implement it, monitor using Perfmon and then see how it goes. As an
aid to avoid contention (data and disk) you might need to consider
staggering synchronization.
Regards,
Paul Ibison SQL Server MVP, www.replicationanswers.com
(recommended sql server 2000 replication book:
http://www.nwsu.com/0974973602p.html)